MedPath

Adjuncts for Adductor Block: Dexamethasone,Dexmedetomidine, or Combination to Reduce Pain

Phase 4
Recruiting
Conditions
ACL Injury
Registration Number
NCT03643822
Lead Sponsor
Women's College Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
252
Inclusion Criteria

Inclusion Criteria:<br><br> - English Speaking<br><br> - ASA 1-3 patients<br><br> - BMI <40<br><br>Exclusion Criteria:<br><br> - Refusal or inability to provide informed consent<br><br> - Any contraindication to regional anesthesia including coagulopathy or bleeding<br> diathesis, allergy to local anesthetics, infection, nerve injury or malignancy at<br> the site of the block<br><br> - History of alcohol/drug dependence<br><br> - History of long term opioid intake or chronic pain disorder<br><br> - History of preexisting neuropathy in the operative leg<br><br> - History of significant psychiatric conditions that may affect patient assessment<br><br> - Inability to understand the informed consent and demands of the study<br><br> - Allergy to any of the components of the multimodal analgesic regimen<br><br> - Revision of ACL repair<br><br> - Diabetes<br><br> - Significant bradycardia (baseline heart rate = 40 beats per minute)

Exclusion Criteria

Not provided

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Oral opioid consumption
Secondary Outcome Measures
NameTimeMethod
Intra-operative opioid consumption;PACU opioid consumption;Time to first analgesic request in PACU;Time to PACU discharge;Visual Analogue Scale-Pain scores - minimum score = 0 and maximum score = 10;Opioid consumption;Risk of block-related complications;Risk of opioid-related side effects;Quality of recovery-15 (QoR15) (0-10, where 0 = none of the time [poor] and 10 = all of the time [excellent];Time to hospital discharge;Time to first analgesic request at home (after discharge);Visual Analogue Scale-Satisfaction scores - where 0 = not satisfied and 10 = very satisfied;Presence/absence of nerve block complications
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