The Effect of Metformin on Neuropathy

Phase 2

Recruiting

• Conditions: Drug-induced Peripheral polyneuropathy.; Drug-induced polyneuropathy; G62.0

• Registration Number: IRCT20190813044526N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 November 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

Non-diabetic patients with histologically confirmed cancer;
scheduled to undergo paclitaxel chemotherapy for cancer.

Exclusion Criteria

Patients with diabetes mellitus;
A history of clinically significant hypersensitivity reaction to medications;
Pregnancy;
Patients who are currently using metformin;
Metformin induced neuropathy at 12 week

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevention of paclitaxel-induced peripheral neuropathy. Timepoint: Before and after intervention (week 12). Method of measurement: Nerve conduction study.

Secondary Outcome Measures

Name	Time	Method
Side effects. Timepoint: Weekly during intervention course. Method of measurement: Taking a history from the patient.