Prophylactic properties of metformin in the prevention of gestational diabetes mellitus
Phase 3
Recruiting
- Conditions
- Gestational Diabetes Mellitus in obese pregnant women.
- Registration Number
- IRCT20200113046112N1
- Lead Sponsor
- Oroumia University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 342
Inclusion Criteria
Age >16 years
Gestational age <3 months
Singleton pregnancy
Body mass index =30
Exclusion Criteria
Multifetal pregnancy
Fetal anomaly
Previous history of diabetes mellitus, gestational diabetes mellitus, impaired fasting glucose or impaired glucose tolerance test
History of corticosteroid use
Heavy alcoholism
History of adverse or allergic reactions to metformin
History of underlying medical conditions (e.g. hypertension, renal failure, liver disease, malabsorption)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of gestational diabetes mellitus. Timepoint: Between weeks 24 and 28 of pregnancy. Method of measurement: Through the performance of two-hour glucose tolerance test with 75 grams of glucose.
- Secondary Outcome Measures
Name Time Method