Comparison of efficacy of extended-release venlafaxine versus sertraline in treatment of patients with major depressive disorder

Not Applicable

• Conditions: Major depressive disorderDepressive episode; extended release venlafaxine; sertraline; Major depressive disorder; Hamilton' s depression questionnaire

• Registration Number: TCTR20160527001
• Lead Sponsor: Ahvaz Jundishapur University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-05-27
• Study Completion: 2016-05-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Terminated (Halted Prematurely)
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

Male or female subjects older than 18 years; Fulfilled DSM IV-TR criteria for major depressive disorder; Baseline score ≧18 on the HDRS-17; no history of antidepressant treatment during current three months.

Exclusion Criteria

Patients who have serious health problems including liver or kidney disease; axis I and II comorbidity; suicidal or killing thoughts; pregnancy; drug hypersensitivity to SSRI or SNRI.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
depression severity week 0, 2 and 4 during intervention the Hamilton Depression Inventory score ( HDRS-17)

Secondary Outcome Measures

Name	Time	Method
the side effects of Sertraline and Extended-release venlafaxine week 0, 2 and 4 according to history and physical examination