Systemic Inflammatory Indices as a Non-invasive Grading Modality for Endometriosis: A Comparative Study Versus Exploratory Laparoscopy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Endometriosis
- Sponsor
- Benha University
- Enrollment
- 88
- Locations
- 1
- Primary Endpoint
- Indices' ability to predict EM stage
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Endometriosis (EMs) is one of the commonest chronic inflammatory disorder affecting women and is characterized by the presence and growth of endometrial-like glandular epithelial and stromal cells outside the uterus leading to multiple clinical symptoms affecting patients quality of life and fertility with high recurrence rate . The systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) are documented as prognostic serum biomarker in many kinds of cancer and for the need and outcomes of adjuvant therapies for various cancers .
Investigators
Ahmed Sabra
Lecturer of Obstetrics & Gynecology Department, Faculty of Medicine.
Benha University
Eligibility Criteria
Inclusion Criteria
- •Women with clinical manifestations suggestive of having EM;
- •Women who was professionally diagnosed;
- •Women who was diagnosed by radiologic workup;
- •Women were free of exclusion criteria.
Exclusion Criteria
- •Women with EM and were maintained on treatment or underwent operative interference during the last three months;
- •Patients had autoimmune diseases, maintained on immunosuppressive therapy for any indication;
- •Women with cancer elsewhere in the body or receiving adjuvant therapies for cancer;
- •Patients receiving therapies for viral disorders especially COVID;
- •Patients refusing to undergo the exploratory laparoscopy.
Outcomes
Primary Outcomes
Indices' ability to predict EM stage
Time Frame: 8 months
Number of patients was diagnosed with EM and got staged right through a calculated indices to the patients who went for exploratory laparoscopy which improve the chances of calculated indices facing the laparoscopy.