A prospective randomised controlled trial investigating three dimensional knee joint kinematics in total knee replacement – a comparison of cruciate retaining, posterior cruciate sacrificing and medially stabilised designs.

Not Applicable

Completed

• Conditions: Osteoarthritis; Musculoskeletal - Osteoarthritis; Surgery - Surgical techniques

• Registration Number: ACTRN12613001278729
• Lead Sponsor: Professor Peter Choong

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-11-19
• Study Completion: 2017-10-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

i) on the waiting list for primary total knee replacement due to osteoarthritis at St Vincent's Hospital, Melbourne
ii) knee replacement performed by one of three joint replacement surgeons at St Vincent's Hospital whose prosthesis of choice is the Medacta GMK Knee System

Exclusion Criteria

i) Surgery for neoplastic disease
ii) Inability to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome will be to assess in vivo three dimensional knee kinematics for three different fixed-bearing total knee replacement prostheses.<br>Joint motion, ground reaction forces and muscle activity will be recorded simultaneously from each subject using an x-ray machine during four test conditions; level walking, stair ascent. stair decent and chair raise. [6 months post operatively ]

Secondary Outcome Measures

Name	Time	Method
imb Alignment - x-ray and computed tomography imaging [6 months post-operatively];Knee Pain and Function <br>-will be measured using the New International Knee Society Score and the Oxford Knee Score Surveys plus a Six-minute-walk-test plus timed-up-go assessments [Pre-operatively, 6 and 12 months post-operatively ]