A study to assess the effectiveness of using high volume ventilation (12-15 mL/kg) in a case of cervical spine injury patients requiring mechanical ventilation, assessed in terms of getting off the ventilatory support as early as possible with fewer complications during the course of ICU stay.
Not Applicable
Completed
- Conditions
- Health Condition 1: S142- Injury of nerve root of cervical spine
- Registration Number
- CTRI/2018/10/016028
- Lead Sponsor
- Department of Neuroanaesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 56
Inclusion Criteria
1. Neurological level of injury C1-C5
2. Date of injury within 3 months of admission in ICU
Exclusion Criteria
1.Any head injury- mild, moderate or severe
2.Chest wall injury
3.Past history of COPD, CHF, ASTHMA, OSA, VAP, ARDS
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine if high tidal volume ventilation strategy facilitates faster weaning from the ventilator compared to low tidal volume ventilation in patients with cervical spine injury (C1-C5)Timepoint: 30 days or till weaning from ventilator is achieved, whichever is earlier
- Secondary Outcome Measures
Name Time Method i. To determine the incidence of atelectasis in both groups. <br/ ><br>ii. To observe the hemodynamics in terms of mean arterial pressure, heart rate and requirement of inotropic support in both groups. <br/ ><br>iii. To determine the incidence of ARDS in both groups <br/ ><br>iv. To determine the incidence of ventilator associated pneumonia in both the groups.Timepoint: Each parameter will be assessed daily