CTRI/2025/08/093458尚未招募Phase 3 4
COMPARISON OF DIFFERENT DOSES OF DEXMEDETOMIDINE AS ADJUVANT TO HYPERBARIC BUPIVACAINE IN SPINAL ANAESTHESIA FOR LOWER LIMB ORTHOPAEDIC SURGERIES
Government Multi Speciality Hospital1 个研究点 分布在 1 个国家目标入组 99 人开始时间: 2025年9月1日最近更新:
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 99
- 试验地点
- 1
- 主要终点
- To determine duration of analgesia
研究概览
简要总结
this is prospective double blind randomised controlled study. In patients, undergoing lower limb surgeries under spinal anaesthesia with hyperbaric bupivacaine, the study will compare the effect of adding two different doses of dexmedetomidine(3 microgram and 5 microgram) to hyperbaric bupivacaine in spinal anaesthesia for lower limb orthopaedic surgeries at government multispeciality hospital ,sec 16A ,chandigarh.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Double
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Age group 18 to 60 years 2)ASA physical status grade I and grade II 3)Weight 50 to 90 kg 4)Height 150 to 180 cm 5)Patients giving consent for the study.
排除标准
- •Patients with any contraindication to regional anaesthesia 2)Patients with a history of significant co existing diseases like uncontrolled diabetes , uncontrolled hypertension, ischaemic heart disease, recent myocardial infarction, heart block, impaired renal functions and severe liver disease.
- •Patients with spine deformities like Kyphoscoliosis, Scoliosis etc.
- •Patient with a history of allergy to the drugs to be used.
- •Patient on alpha2 agonist or antagonist therapy.
结局指标
主要结局
To determine duration of analgesia
时间窗: 12 Hours
次要结局
- 1)To determine the onset and duration of sensory and motor blockade(2)To study the effect on haemodynamic parameters.)
研究者
Lalit kumar
Government Multi Speciality Hospital- 16, CHANDIGARH
研究点 (1)
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