Effectiveness of Atypical Versus Conventional Antipsychotics in Treating Schizophrenia

Phase 4

Completed

• Conditions: Schizophrenia

• Registration Number: NCT00237861
• Lead Sponsor: Yale University

Brief Summary

This study will compare the effectiveness of newer atypical antipsychotics versus older conventional antipsychotics in treating schizophrenia.

Detailed Description

At seven participating hospitals, acutely exacerbated patients with schizophrenia were randomly assigned to treatment with antipsychotic from the atypical class vs antipsychotic from the conventional class. Medication choice within class, dose, concomitant medications, and other prescribing decisions were left to the community prescriber. Patients were followed for one year after discharge.

Study Timeline

• Primary Completion: 2002-12
• Study First Submitted: 2005-10-07
• Study First Submitted QC: 2005-10-07
• Study First Posted: 2005-10-12
• Status Verified: 2014-06
• Last Update Submitted: 2014-06-05
• Last Update Posted: 2014-06-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• hospitalized for schizophrenia

Exclusion Criteria

• none

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
PANSS
Retention.

Secondary Outcome Measures

Name	Time	Method
EPS, TD.