Evaluation of maximum cross-section of extraocular muscles and orbital fat volume using 3T MRI.
Not Applicable
- Conditions
- thyroid-associated ophthalmopathy extraocular muscular atrophy
- Registration Number
- JPRN-UMIN000012492
- Lead Sponsor
- Hiroshima University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
(a) Contraindication to MRI(cardiac pacemaker; cochlear implantation device; defibrillator; neurostimulator; bone growth stimulation device; infusion pump; deep brain stimulation; cervical artery crump(Poppen-Blaylock); chip of ferromagnetic substance in eyeball, brain, internal organs, lung, mediastinum; intraaortic filter, intravascular coil or stent within 2 months, claustrophobia, tattoo, pregnancy or likelihood of pregnancy) (b) People who were unsuitable for this study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method A comparison of maximum cross-section of extraocular muscles and orbital fat volume of patients with thyroid-associated ophthalmopathy at before and after treatment.
- Secondary Outcome Measures
Name Time Method (a) The association between CAS (clinical activity score) and maximum cross-section of extraocular muscles/ orbital fat volume of patients with thyroid-associated ophthalmopathy. (b) A comparison of maximum cross-section of extraocular muscles between patients with thyroid-associated ophthalmopathy, patients with extraorbital muscular atrophy and controls. (c) A comparison of orbital fat volume between patients with thyroid-associated ophthalmopathy and controls.