The effect of of intravenus Lidocaine in comparision with oral Clonidine on heart rate and blood pressure after tracheal intubation in paitients undergo elective surgury with general anesthesia

Phase 2

• Conditions: Paitients undergo direct laryngoscopy and tracheal intubation with general anesthesia.; Other complications of surgical and medical care, not elsewhere classified

• Registration Number: IRCT2014102819731N1
• Lead Sponsor: Tehran University of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 86

Inclusion Criteria

Inclusion criteria( patients older than 18 years old ; with ASA class I and II).Exclusion criteria ( patients taking drugs that affect hemodynamic or autonomic system ; obese patients(BMI>35) ; patients who have difficult airway(3 miller's criteria +) ; hypovolumic patient ; coronary arteries diseases ; respiratory; renal ; cerebral diseases ; pheochromocytoma ; hypo or hyperthyroidism ; electrocardiographic disturbances ; CHF ,diabetus mellitus ; ,uncontrolled hypertension ; mallampati ; history of allergy or contraindication for drugs used in this study ; pregnant women ; and also patients with more than one laryngoscopic trying for intubation ) .

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic blood presure. Timepoint: 5 minute before induction,just before laryngoscopy and 1-3-5-10 minutes after laryngoscopy and tracheal intubation. Method of measurement: blood presure manometer in mmHg.;Diastolic blood presure. Timepoint: 5 minute before induction,just before laryngoscopy and 1-3-5-10 minutes after laryngoscopy and tracheal intubation. Method of measurement: blood presure manometer in mmHg.;Mean arterial blood presure. Timepoint: 5 minute before induction,just before laryngoscopy and 1-3-5-10 minutes after laryngoscopy and tracheal intubation. Method of measurement: blood presure manometer in mmHg.;Heart rate. Timepoint: 5 minute before induction,just before laryngoscopy and 1-3-5-10 minutes after laryngoscopy and tracheal intubation. Method of measurement: counting heart ratenting.