Development of Machine Learning Models for the Prediction of Complications After Colonic, Colorectal and Small Intestine Anastomosis in Psychiatric and Non-psychiatric Patient Collectives (P-Study)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Complications
- Sponsor
- Dr. Med Anas Taha
- Enrollment
- 10000
- Locations
- 1
- Primary Endpoint
- Complication after surgery/ Comprehensive Complication Index/ Clavian Dindo Score
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Our study aims to lay the basis for a predictive modeling service for postoperative complications and prolonged hospital stay in patients suffering from psychiatric diseases undergoing colorectal surgery.
Furthermore, we aim to investigate the impact of preoperative Risk factors, psychiatric and psychosomatic diseases on the outcomes of colorectal surgery and the complications after colorectal surgeries like anastomosis insufficiency via predictive modeling techniques
The service mentioned above will be publicly available as a web-based application
Investigators
Dr. Med Anas Taha
Research Fellow
University of Basel
Eligibility Criteria
Inclusion Criteria
- •Colocolic, colorectal and small intestine anastomosis
- •Neoplasia,
- •Diverticulitis
- •Mesenteric ischemia
- •Iatrogenic or traumatic perforation
- •Inflammatory bowel disease
Exclusion Criteria
- •Patients \<18 years
- •Patients suffering from recurrent colorectal cancer bearing
- •Peritoneal carcinomatosis or unresectable metastatic disease at the time of bowel resection and anastomosis will be excluded.
- •Patients who cannot be followed up on for more than six weeks after surgery
Outcomes
Primary Outcomes
Complication after surgery/ Comprehensive Complication Index/ Clavian Dindo Score
Time Frame: From index surgery up to six weeks postoperatively
Impact of psychatric and psychosomatic disorders are having higher complication rates
Intraoperative influid manangment
Time Frame: Time Frame: From index surgery up to six weeks postoperatively
Impact of Intraoperative influid on the development of anastomotic insuffiency
Length of Hospital Stay (in Days)
Time Frame: From surgery up to 12 weeks postoperatively
Impact of psychatric and psychosomatic disorders are having longer hospitalization
Development of a preoperative score for morbidity/mortality in colorectal surgery
Time Frame: From index surgery up to six weeks postoperatively
Check the risk for morbidity/mortality in colorectal surgery
Anastomotic insufficiency/leakage
Time Frame: From index surgery up to six weeks postoperatively
Predictive model with an app for the development of anastomosis insufficiency based on the risk factors.