跳至主要内容
临床试验/NCT04092933
NCT04092933进行中(未招募)不适用

Machine-learning Model for Perioperative Risk Calculation

Technical University of Munich0 个研究点目标入组 175,559 人开始时间: 2014年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
175,559
主要终点
postoperative complications

研究概览

简要总结

The aim of this project is to develop a machine-learning model for calculating the risk of postoperative complications. In addition to the data collected during the premedication, the model will include all intraoperative values recorded in the Patient Data Management System (PDMS), which include not only vital and respiratory parameters, but also medication and doses, intraoperative events and times. Postoperative complications are defined according to their severity according to the Clavien-Dindo score (Dindo, Demartines et al., 2004) and are collected from the data available in the health information system (HIS).

The machine-learning model is created using an extreme-gradient boosting algorithm which has been updated with new data from the year 2021 to ensure accuracy of the model.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • all patients who underwent surgery with anesthesia

排除标准

  • 未提供

结局指标

主要结局

postoperative complications

时间窗: 30 days

Postoperative complications are classified by means of the Clavien-Dindo-Score. The Clavien-Dindo-Score describes classes of severity of postoperative complications: Grade I: any deviation from the normal postoperative course without the need for pharmacological treatment or surgical, endoscopic and radiological interventions Grade II: requiring pharmacological treatment Grade IIIa: requiring surgical, endoscopic or radiological intervention not under general anesthesia Grade IIIb: requiring surgical, endoscopic or radiological intervention under general anesthesia Grade IVa: single organ dysfunction Grade IVb: multiorgandysfunction Grade V: death of a patient

次要结局

  • in-hospital mortality(30 days)

研究者

发起方
Technical University of Munich
申办方类型
Other
责任方
Sponsor

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