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Clinical Trials/NCT04092933
NCT04092933
Active, not recruiting
Not Applicable

Machine-learning Model for Perioperative Risk Calculation

Technical University of Munich0 sites175,559 target enrollmentMay 1, 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Perioperative/Postoperative Complications
Sponsor
Technical University of Munich
Enrollment
175559
Primary Endpoint
postoperative complications
Status
Active, not recruiting
Last Updated
2 years ago

Overview

Brief Summary

The aim of this project is to develop a machine-learning model for calculating the risk of postoperative complications. In addition to the data collected during the premedication, the model will include all intraoperative values recorded in the Patient Data Management System (PDMS), which include not only vital and respiratory parameters, but also medication and doses, intraoperative events and times. Postoperative complications are defined according to their severity according to the Clavien-Dindo score (Dindo, Demartines et al., 2004) and are collected from the data available in the health information system (HIS).

The machine-learning model is created using an extreme-gradient boosting algorithm which has been updated with new data from the year 2021 to ensure accuracy of the model.

Registry
clinicaltrials.gov
Start Date
May 1, 2014
End Date
December 31, 2024
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Technical University of Munich
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • all patients who underwent surgery with anesthesia

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

postoperative complications

Time Frame: 30 days

Postoperative complications are classified by means of the Clavien-Dindo-Score. The Clavien-Dindo-Score describes classes of severity of postoperative complications: Grade I: any deviation from the normal postoperative course without the need for pharmacological treatment or surgical, endoscopic and radiological interventions Grade II: requiring pharmacological treatment Grade IIIa: requiring surgical, endoscopic or radiological intervention not under general anesthesia Grade IIIb: requiring surgical, endoscopic or radiological intervention under general anesthesia Grade IVa: single organ dysfunction Grade IVb: multiorgandysfunction Grade V: death of a patient

Secondary Outcomes

  • in-hospital mortality(30 days)

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