The putative role of keratoconjunctivitis sicca in the development of blepharoptosis.

Completed

• Conditions: drooping eye lid; 10030046

• Registration Number: NL-OMON30204
• Lead Sponsor: Oogziekenhuis Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

Group 1 (ptosis):
- Diagnosis of gradually developed unilateral or bilateral ptosis of the upper eye lid.
- Age >= 40 years for patients not wearing contact lens(es) in affected eye(s).
- Age >= 20 years for patients wearing contact lens(es) in affected eye(s).
- Vertical eyelid fissure <= 7 mm in primary position.
- Bilateral levator function > 10 mm.;Group 2 (no ptosis):
- Age >= 40 years for patients not wearing contact lens(es).
- Age >= 20 years for patients wearing contact lens(es).
- Vertical eyelid fissure > 7 mm in primary position.
- Bilateral levator function > 10 mm.
- Age and gender match to a patient from group 1 ( |*age| < 5 years ).

Exclusion Criteria

Group 1 (ptosis):
- Neurological disorder.
- Muscular disorder.
- Suspicion of other possible cause.;Group 2 (no ptosis):
- Neurological disorder.
- Muscular disorder.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Significant difference in proportion of patients with dry eyes between groups<br /><br>(*2, a=0.05).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Schirmer-2 score, tear break-up time, corneal staining, degree of ptosis,<br /><br>record of possible risk factors (previous trauma, contact lens wear, ocular<br /><br>surgery, subjective complaints, punctate keratitis, blepharitis, etc.).</p><br>