IS ADDITION OF IRRIGATION OF WOUND WITH NORMAL SALINE TO VACUUM THERPAY MORE EFFECTIVE IN HEALING OF EXTREMITY ULCER COMPARED TO CONVENTIONAL VACUUM THERAPY
Phase 4
Completed
- Conditions
- Health Condition 1: S818- Open wound of lower leg
- Registration Number
- CTRI/2020/05/025410
- Lead Sponsor
- Jawaharlal Institute of Postgraduate Medical Education and Research JIPMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 48
Inclusion Criteria
extremity ulcer
Exclusion Criteria
1. Patients with uncontrolled hyperglycaemia (HbA1c > 12%)
2. Patients with peripheral vascular disease
3. Patients on concomitant drug therapy such as immunosuppressant, corticosteroids.
4.Patients with underlying malignancy
5. Active necrotising fasciitis
6. Wounds with open joint capsules
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie wound healing enhancement by normal saline instillation in NPWT for lower leg ulcers?
How does NPWT with normal saline compare to standard-of-care wound dressings in extremity ulcer healing rates?
Are there specific biomarkers that predict response to NPWT with saline instillation in S818 lower leg ulcers?
What adverse events are associated with NPWT saline instillation versus conventional NPWT in wound management?
What combination therapies with NPWT have shown improved outcomes for chronic lower extremity ulcers in clinical studies?