Observation of a Protein molecule in precancer diseases that may predict conversion into oral cancer
Not Applicable
- Conditions
- Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
- Registration Number
- CTRI/2024/05/067042
- Lead Sponsor
- Institute of Dental Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Tissue samples of OPMDs that have been verified histopathologically
2 Tissue samples of OVC & OSCC that have been verified histopathologically
Exclusion Criteria
1 Insufficient clinical data
2 Tissues where controls exhibit unexpected results
3 Tissue samples that do not contain enough biological material for an immunohistochemistry analysis to be done
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Immunohistochemical expression for CLIC4 in Oral Potentially malignant disorders will be statistically low as compared to its expression in Oral verrucous carcinoma and Oral squamous cell carcinoma.Timepoint: Immunohistochemical staining expression will be evaluated Once only after CLIC4 staining procedure.
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI