The effect of Daucus carota spp. carota seed extract & Persian Medicine Life style modifications on spermograms of men with idiopathic infertility

Phase 3

Recruiting

• Conditions: Idiopathic Male Infertility.; Male infertility

• Registration Number: IRCT20210911052430N1
• Lead Sponsor: Gorgan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 96

Inclusion Criteria

1. Men 20-50 years with at least one year of idopatic infertility disorder
2. Existence of at least one of the three criteria related to sperm disorder (number - motility - morphology) - Existence of idiopathic oligospermia disorder according to WHO criteria (Existence of sperm count less than 15 million per ml and total less than 39 million in semen It is called oligospermia) - Presence of idiopathic stenospermia according to WHO criteria (if the percentage of sperm with normal motility in semen is less than 40% is called stenospermia). Has a normal morphology in semen less than 4% is called teratospermia)
3. Patients with varicocele who has been 6 month since their surgery and have not been able to conceive
4. Normal testosterone, serum gonadotropins and prolactin
5. Normal thyroid hormones (no hypo or hypothyroidism)
6. BMI=30kg/m2
7. Satisfaction of the patient

Exclusion Criteria

1- Severe oligospermia or azoospermia (less than 5 million sperm per milliliter)
2- History of epididymitis, prostatitis, trauma, testicular torsion, inguinal scrotal surgery
3- Pretesticular disorders such as endocrine diseases (hyperprolactinemia, congenital adrenal hyperplasia ...)
4- Known Testicular disorders such as varicocele or orchitis or cryptorchidism
5- Known post testicular disorders such as mechanical obstruction, impaired egg transfer or functional obstruction, vasectomy, etc.
6- History of taking anti-metabolites and alkylators
7- History of cancer and chemotherapy and radiotherapy treatments
8- Having chronic diseases such as diabetes and cardiovascular disorders
9- Infection of the genital tract
10- Taking cytotoxic, immunosuppressive, androgen or anti-androgen drugs and alcohol or opium addiction
11- Having liver failure
12- Having kidney failure
13- History of receiving medicine for infertility treatment in the last three months
14- History of receiving drugs affecting semen in the last three months

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean semen volume (cc). Timepoint: Beginning and end of the study. Method of measurement: Use a pipette or calibrated tube.;Mean sperm count per milliliter of semen. Timepoint: Beginning and end of the study. Method of measurement: Sperm analyzer and neobar slide.;Mean percentage of motile sperms. Timepoint: Beginning and end of the study. Method of measurement: Sperm analyzer device and simple slide.;Mean sperm percentage with normal morphology. Timepoint: Beginning and end of the study. Method of measurement: Sperm analyzer device and simple slide.;Sexual function. Timepoint: Beginning and end of the study. Method of measurement: Men's Sexual Health Questionnaire.