To evaluate the effect of Metoclopramide -a prokinetic and anti emetic drug on the gastric volume after adequate fasting in patients undergoing gynaecological surgeries after spinal anaesthesia

Not yet recruiting

• Conditions: Abnormal uterine and vaginal bleeding, unspecified, (2) ICD-10 Condition: N819||Female genital prolapse, unspecified, (3) ICD-10 Condition: N72||Inflammatory disease of cervix uteri,

• Registration Number: CTRI/2024/04/066529
• Lead Sponsor: Dr RPGMC Kangra at Tanda

Brief Summary

this study will assess the effectiveness of preoperative injection metoclopramide on the gastric residual volume with the help of US guided assessment of gastric residual volume at baseline and 30 minutes after the drug. This study will also observe the effect of fasting duration on gastric volume

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-04-27
• Study Start: 2024-10-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

ASA class I and II BMI 18.5 – 29.9 kg/m2 Mallampati I or II.

Exclusion Criteria

• 1.Patients’ refusal for SAB 2.
• Patients with cardiovascular or respiratory disorders, diabetes, hypertension 3.Obesity( BMI>29.9kg/m2) 4.Abnormality of upper gastrointestinal tract(GIT) and history of GIT related surgical procedures in the past 5.Use of drugs affecting gastric motility 6.
• Need for general anaesthesia (GA) due to partial effect of SAB 7.Any contraindication to SAB 8.Cognitive impaired patients 9.History of prolonged QT interval or neuropsychiatric illness.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome will be to observe the quantitative and qualitative change in gastric antrum as assessed by the US of gastric antrum to estimate gastric volume after standard dose of metoclopramide ie calculation of CSA in right lateral and supine position	baseline and 30 minutes after intervention

Secondary Outcome Measures

Name	Time	Method
1.Incidence of complete gastric emptying	2.Incidence of episodes of intraoperative and postoperative nausea and vomiting after gynaecological surgeries correlated with Metoclopramide administration and gastric volume

Trial Locations

Locations (1)

Dr Rajendra Prasad Government Medical College Kangra at Tanda; 🇮🇳 Kangra, HIMACHAL PRADESH, India

Dr Rajendra Prasad Government Medical College Kangra at Tanda

🇮🇳Kangra, HIMACHAL PRADESH, India

Dr Alisha Katwal

Principal investigator

alishakatwal3@gmail.com