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Observational Study to Evaluate Efficacy, Safety and Tolerability of Z-n-butylresorcinol in Patients with Melasma

Not Applicable
Completed
Conditions
Melasma
Registration Number
CTRI/2015/04/005697
Lead Sponsor
Micro Labs Ltd
Brief Summary

This study is Open Label,Single Arm, Observational Study to Evaluate Efficacy, Safety and Tolerabilityof 4-n-butylresorcinol in 50 subjects with  Melasma. The study conducted at two sites inIndia. The primary outcome measures efficacy of 4-n-butylresorcinol in reducingmelasma and the secondary outcome measures safety  and tolerability of 4-n-butylresorcinol bythe investigators. The total treatment period is 8 weeks

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
50
Inclusion Criteria

•Subjects with melasma who are either treatment naive or were not on any treatment for at-least 6 months •Subjects aged 18 and above years with melasma •Subjects with Epidermal type of melasma •Subjects with Fitzpatrick skin types III, IV and V •Subjects willing to apply sunscreen during the course of study •Subjects willing to return for all clinic visits and complete all study-related procedures.

Exclusion Criteria

Not provided

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Evaluate the efficacy of 4-n-butylresorcinol in reducing melasma4th week and 8th Week
Secondary Outcome Measures
NameTimeMethod
Evaluate safety of 4-n-butylresorcinol based on the adverse effects as mentioned by the patient and evaluated by the investigator.Assess tolerability of 4-n-butylresorcinol by the investigators

Trial Locations

Locations (2)

Dr.B.R Ambedkar Medical college

🇮🇳

Bangalore, KARNATAKA, India

Kempegowda Institute of Medical Sciences

🇮🇳

Bangalore, KARNATAKA, India

Dr.B.R Ambedkar Medical college
🇮🇳Bangalore, KARNATAKA, India
DrMadan Mohan
Principal investigator
080-25476498
derma_madanmohan@yahoo.co.in

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