Breaking the Barrier: CD8+ T cells in Atopic Dermatitis and Psoriasis Vulgaris - CD8+ T cells in Atopic Dermatitis and Psoriasis Vulgaris

niversitair Medisch Centrum Utrecht0 个研究点目标入组 36 人开始时间: 待定最近更新: 2024年8月12日

适应症

试验速览

暂无简介。

•Atopic dermatitis patients:
•- Adult (18-70 years of age) male or female patients diagnosed with atopic dermatitis
•- Positive APT to house dust mite allergen
•- Biopsy location (~4 cm2) should not be treated with topical steroids for at least 1 week
•- No use of oral antihistamines in the 2 weeks prior to inclusion;Psoriasis vulgaris patients:
•- Adult (18-70 years of age) male or female patients diagnosed with psoriasis vulgaris
•- Biopsy location (~4 cm2) should not be treated with topical steroids for at least 1 week;Healthy controls:
•- Adult (18-70 years of age) male or female volunteers without a history of skin diseases
•- Biopsy location (~4 cm2) should not be treated with topical steroids for at least 1 week
•- No history of asthma and/or hay fever

•- Use of systemic immunosuppressive drugs (i.e., cyclosporin, prednisolone, methotrexate, neotigason, fumaric acid) in the 6 weeks prior to inclusion
•- Exposure of biopsy location to (extraordinary) UV sunlight (i.e. UV-therapy, sunny holiday) in the weeks prior to inclusion
•- (Secondary) skin infection

发起方

niversitair Medisch Centrum Utrecht