The Prevalence of Malnutrition and Sarcopenia in Swiss Rehabilitation Settings
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 550
- 试验地点
- 5
- 主要终点
- Body weight
研究概览
简要总结
The aim of the study is to identify the prevalence of malnutrition and sarcopenia in patients admitted in Swiss rehabilitation centers. Furthermore, the aim is to investigate the changes of selected malnutrition and sarcopenia parameters over the length of the rehabilitation stay.
详细描述
The project aims to investigate the prevalence of malnutrition and sarcopenia in the rehabilitation setting. A cross-sectional national multicenter study will be conducted in five rehabilitation centers in Switzerland, including 80 - 130 participants per center for the primary objective (prevalence study). Patients will be screened for malnutrition and sarcopenia with established screening tools and if an elevated risk is observed, diagnosis will be confirmed and severity investigated according to international guidelines. Furthermore, the evolution of selected malnutrition and sarcopenia parameters over the rehabilitation stay should be assessed.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients treated in the following groups of rehabilitations will be included:
- •Geriatric rehabilitation
- •Pulmonal rehabilitation
- •Cardiovascular rehabilitation
- •Neurological rehabilitation
- •Musculoskeletal rehabilitation
- •Internistic rehabilitation and oncological rehabilitation
- •Exclusion criteria:
- •Inability to give informed consent
- •Inability to follow study procedures (e.g., due to delirium or language barriers)
- •Expected life expectancy < 3 months and/or palliative care
- •Isolation for example due to Covid-19 infection or tuberculosis
- •Severe dehydration/ volume overload
- •Medical conditions that prevent conducting a Bioelectrical Impedance Analysis (BIA) measurement (e.g. non-removable plasters or bandages at feet or hands) or defibrillator
排除标准
- 未提供
结局指标
主要结局
Body weight
时间窗: Within 7 days after admission
(in kg)
Height
时间窗: Within 7 days after admission
(in cm)
Prevalence of malnutrition - Risk for malnutrition
时间窗: Within 7 days after admission
The risk for malnutrition will be screened by the Nutritional Risk Screening (NRS-2002, in points). NRS has a scale from 0 to 7 points; higher points indicate a higher risk for malnutrition.
Body Mass Index
时间窗: Within 7 days after admission
(calculated by weight and height in kg/m2)
Muscle mass by Bioelectrical Impedance Analysis (BIA) - Part 2
时间窗: Within 7 days after admission
Resistance (in Ohm) and Reactance (in Ohm) measured with BIA are combined with further information on weight, height, sex and age to calculate the appendicular skeletal muscle mass index (in kg/m2)
Weight loss
时间窗: Within 7 days after admission
Weight loss (in percent in six categories - \<5 percent within the last 6 months, 5-10 percent within the last 6 months, \>10 percent within the last 6 months; \<10 percent in more than 6 months, 10 -20 percent in more than 6 months, \>20 percent in more than 6 months)
Reduced energy intake
时间窗: Within 7 days after admission
Reduced energy intake (in percent of intake versus requirement in three categories: less than 50 percent of energy requirement covered for more than 1 week, any reduced energy intake versus requirement for \>2 weeks, no reduced energy intake)
Muscle mass by Bioelectrical Impedance Analysis (BIA) - Part 1
时间窗: Within 7 days after admission
Resistance (in Ohm) and Reactance (in Ohm)
Prevalence of malnutrition - Confirmed diagnosis and severity of malnutrition
时间窗: Within 7 days after admission
In case of positive screening, diagnosis of malnutrition will be confirmed and severity assessed according to the Global Leadership Initiative on Malnutrition (GLIM) criteria using the following measures described above: weight (in kg); height (in cm); Body Mass Index (calculated by weight and height in kg/m2); weight loss (in percent in six categories - \<5 percent within the last 6 months, 5-10 percent within the last 6 months, \>10 percent within the last 6 months; \<10 percent in more than 6 months, 10 -20 percent in more than 6 months, \>20 percent in more than 6 months); reduced energy intake (in percent of intake versus requirement in three categories: less than 50 percent of energy requirement covered for more than 1 week, any reduced energy intake versus requirement for \>2 weeks, no reduced energy intake); Bioelectrical impedance analysis for muscle mass: resistance (in Ohm), reactance (in Ohm), Appendicular skeletal muscle mass index (in kg/m2)
Prevalence of malnutrition - overall
时间窗: Calculated through study completion after five months recruitment duration
Overall prevalence of malnutrition will be reported in percent
次要结局
- Prevalence of sarcopenia - Diagnosis of sarcopenia(Within 7 days after admission)
- Prevalence of sarcopenia - Risk for sarcopenia by SARC-F(Within 7 days after admission)
- Prevalence of sarcopenia - Risk for sarcopenia by handgrip strength(Within 7 days after admission)
- Prevalence of sarcopenia - Risk for sarcopenia(Within 7 days after admission)
- Prevalence of sarcopenia - Severity of sarcopenia(Within 7 days after admission)
- Prevalence of sarcopenia - Overall(Calculated through study completion after five months recruitment duration)
- Changes of handgrip strength between admission and discharge of rehabilitation(At admission and 21 days after admission (or, if admission occurs before 21 days and the length of stay was at least 14 days than within 3 days before discharge))
- Changes of body weight between admission and discharge of rehabilitation(At admission and 21 days after admission (or, if admission occurs before 21 days and the length of stay was at least 14 days than within 3 days before discharge))
- Changes of BMI between admission and discharge of rehabilitation(At admission and 21 days after admission (or, if admission occurs before 21 days and the length of stay was at least 14 days than within 3 days before discharge))
- Changes of Functional Independence Measure between admission and discharge of rehabilitation(At admission and 21 days after admission (or, if admission occurs before 21 days and the length of stay was at least 14 days than within 3 days before discharge))
研究者
Undine Lehmann, Dr.
Lecturer
Bern University of Applied Sciences