Prevalence of Sarcopenia and Undernutrition in Patients With Cirrhosis and Abdominal Hernia

Completed

• Conditions: Malnutrition; Sarcopenia; Cirrhosis; Hernia, Abdominal
• Interventions: Diagnostic Test: Computed Tomography Scan

• Registration Number: NCT03458845
• Lead Sponsor: University of Sao Paulo

Brief Summary

The study evaluates whether sarcopenia influences the prevalence of abdominal hernias in patients with cirrhosis.

Detailed Description

Sarcopenia is a common condition in patients with cirrhosis, with a prevalence of around 50%. It is unknown if the presence of sarcopenia may influence the prevalence of abdominal hernias in this group of patients. Clinical, nutritional and radiological evaluation will be performed in two groups of cirrhotic patients to evaluate this hypothesis.

Study Timeline

• Study First Submitted: 2018-02-26
• Study First Submitted QC: 2018-03-01
• Study First Posted: 2018-03-08
• Study Start: 2018-05-30
• Primary Completion: 2021-01-15
• Status Verified: 2021-04
• Study Completion: 2021-04-20
• Last Update Submitted: 2021-04-26
• Last Update Posted: 2021-04-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• ≥ 18 years
• Previous diagnosis of cirrhosis

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Exclusion Criteria

• Acutely decompensated cirrhosis
• Other chronic diseases in advanced stage (e.g. cardiac failure, chronic obstructive pulmonary disease, cancer)
• Cognitive impairment, delirium, non-controlled psychosis

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 1	Computed Tomography Scan	This group consists of cirrhotic patients with any abdominal hernia
Group 2	Computed Tomography Scan	This group consists of cirrhotic patients without any hernias

Primary Outcome Measures

Name	Time	Method
Prevalence of Sarcopenia	Through study completion (an average of 1 year)	Prevalence of Sarcopenia in patients with cirrhosis
Influence of Sarcopenia in Prevalence of Abdominal Hernias in Patients with Cirrhosis	Through study completion (an average of 1 year)	Influence of Sarcopenia in Prevalence of Abdominal Hernias in Patients with Cirrhosis

Trial Locations

Locations (1)

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo; 🇧🇷 São Paulo, SP, Brazil