Sarcopenia After Bariatric Surgery in Older Patients: a Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- The number of older patients with sarcopenia after bariatric surgery compared to non-surgical control patients.
研究概览
简要总结
The retrospective cohort study will compare the prevalence of sarcopenia and associated factors between older patients who have undergone bariatric surgery and older patients with obesity without previous bariatric surgery.
详细描述
The aim of the study is to compare the prevalence of sarcopenia and nutritional status between adults older than 65 years who have previously undergone bariatric surgery and patients with obesity but without previous bariatric surgery. Current sarcopenia will be assessed during a cross-sectional assessment after surgery using the criteria from the European Working Group on Sarcopenia in Older People (EWGSOP).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Signed informed consent
- •Age 65 years or older
- •Cohort 1 (exposed): Previous bariatric surgery for obesity at least 1 one year ago
- •Cohort 2 (unexposed): No previous weight loss surgery
排除标准
- •Current diagnosis of cancer
- •Advanced organ failure, including chronic kidney disease Stage 5, liver cirrhosis Stage 3, intestinal failure, heart failure stage D, or chronic obstructive pulmonary disease stage
- •Immobility
- •Neuromuscular degenerative conditions
结局指标
主要结局
The number of older patients with sarcopenia after bariatric surgery compared to non-surgical control patients.
时间窗: At least one year post surgery
a) Sarcopenia will be classified according to the criteria form the European Working Group on Sarcopenia in Older People revised guidelines (EWGSOP2) based on skeletal muscle mass, muscle strength and physical performance criteria.
次要结局
- 3. Markers of chronic systemic inflammation in older patients after bariatric surgery compared to non-surgical control patients(At least one year post surgery)
- 1. Appendicular skeletal muscle mass older of patients after bariatric surgery compared to non-surgical control patients(At least one year post surgery)
- 2. The prevalence of nutrient deficiencies in older patients after bariatric surgery compared to non-surgical control patients.(At least one year post surgery)