Sarcopenia After Bariatric Surgery in Older Patients: a Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Overweight and Obesity
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- The number of older patients with sarcopenia after bariatric surgery compared to non-surgical control patients.
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The retrospective cohort study will compare the prevalence of sarcopenia and associated factors between older patients who have undergone bariatric surgery and older patients with obesity without previous bariatric surgery.
Detailed Description
The aim of the study is to compare the prevalence of sarcopenia and nutritional status between adults older than 65 years who have previously undergone bariatric surgery and patients with obesity but without previous bariatric surgery. Current sarcopenia will be assessed during a cross-sectional assessment after surgery using the criteria from the European Working Group on Sarcopenia in Older People (EWGSOP).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Signed informed consent
- •Age 65 years or older
- •Cohort 1 (exposed): Previous bariatric surgery for obesity at least 1 one year ago
- •Cohort 2 (unexposed): No previous weight loss surgery
Exclusion Criteria
- •Current diagnosis of cancer
- •Advanced organ failure, including chronic kidney disease Stage 5, liver cirrhosis Stage 3, intestinal failure, heart failure stage D, or chronic obstructive pulmonary disease stage
- •Immobility
- •Neuromuscular degenerative conditions
Outcomes
Primary Outcomes
The number of older patients with sarcopenia after bariatric surgery compared to non-surgical control patients.
Time Frame: At least one year post surgery
a) Sarcopenia will be classified according to the criteria form the European Working Group on Sarcopenia in Older People revised guidelines (EWGSOP2) based on skeletal muscle mass, muscle strength and physical performance criteria.
Secondary Outcomes
- 3. Markers of chronic systemic inflammation in older patients after bariatric surgery compared to non-surgical control patients(At least one year post surgery)
- 1. Appendicular skeletal muscle mass older of patients after bariatric surgery compared to non-surgical control patients(At least one year post surgery)
- 2. The prevalence of nutrient deficiencies in older patients after bariatric surgery compared to non-surgical control patients.(At least one year post surgery)