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临床试验/NCT05323604
NCT05323604已完成不适用

Impact of Sarcopenia on Post-operative Course for Cancer Patients Operated of Colorectal Surgery Using a Simple Measurement Method of the Psoas Muscle Surface Area

Hôpital NOVO1 个研究点 分布在 1 个国家目标入组 58 人开始时间: 2022年3月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
58
试验地点
1
主要终点
Comparison of the average postoperative length of stay in sacopenic and non-sarcopenic patients

研究概览

简要总结

The purpose of this study is to compare the post-operative course in patients suffering from sarcopenia who had colorectal surgery for cancer. Our primary outcome is the comparaison of the length of hospital stay in sarcopenic and non sarcopenic patients.

详细描述

Sarcopenia is the loss of muscle mass that occurs usually with aging, but it may have multiple contributing factors, especially related to chronic diseases such as colorectal cancer.

When present, sarcopenia is predictive of poor post-operative course. The identification of sarcopenia needs either the identification of low muscle strength, low muscle quantity/quality, or finally a low physical performance.

Multiple clinical, biological or radiological tools were proposed. Our purpose is to compare the post-operative outcome of sarcopenic and non sarcopenic patients using a simple, available, reproducible and rapid radiological method, which will help the healthcare professionals to rapidly identify high risk patients for possible complicated and long post-operative course allowing them to take appropriate perioperative measures to reduce the risks.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patient operated on for colectomy or proctectomy with restoration of continuity for colorectal cancer between 1 January 2020 and 31 December 2021
  • Patient who had a CT scan in the 2 months prior surgery
  • Patient aged 18 years or older

排除标准

  • Patients with inflammatory bowel disease (Crohn disease, haemorrhagic rectocolitis)
  • Patients with neuromuscular pathology affecting their mobility
  • Patients who were diagnosed positif to SARS COV 2 before or during hospitalisation
  • Patients who refuse the collection of their data

结局指标

主要结局

Comparison of the average postoperative length of stay in sacopenic and non-sarcopenic patients

时间窗: Until discharge from hospital, an average of 30 days

Comparison of the number of post-operative hospital days between the two groups

次要结局

  • Comparison between complication rate in sarcopenic and non sarcopenic patients(At the end of the 30 post-operative days)
  • Assessment of re-hospitalization rate between sarcopenic and non sarcopenic patients(At the end of the 30 post-operative days)
  • Comparison of the length of stay in the rehabilitation center for sarcopenic and non sarcopenic transferred patients(At the end of the 30 post-operative days)
  • Comparison of the transfer rate to rehabilitation or nursing home center between sarcopenic and non sarcopenic patients(At the end of the 30 post-operative days)

研究者

发起方
Hôpital NOVO
申办方类型
Other
责任方
Sponsor

研究点 (1)

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