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Clinical Trials/NCT05323604
NCT05323604
Completed
Not Applicable

Impact of Sarcopenia on Post-operative Course for Cancer Patients Operated of Colorectal Surgery Using a Simple Measurement Method of the Psoas Muscle Surface Area

Hôpital NOVO1 site in 1 country58 target enrollmentMarch 1, 2022
ConditionsSarcopenia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sarcopenia
Sponsor
Hôpital NOVO
Enrollment
58
Locations
1
Primary Endpoint
Comparison of the average postoperative length of stay in sacopenic and non-sarcopenic patients
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The purpose of this study is to compare the post-operative course in patients suffering from sarcopenia who had colorectal surgery for cancer. Our primary outcome is the comparaison of the length of hospital stay in sarcopenic and non sarcopenic patients.

Detailed Description

Sarcopenia is the loss of muscle mass that occurs usually with aging, but it may have multiple contributing factors, especially related to chronic diseases such as colorectal cancer. When present, sarcopenia is predictive of poor post-operative course. The identification of sarcopenia needs either the identification of low muscle strength, low muscle quantity/quality, or finally a low physical performance. Multiple clinical, biological or radiological tools were proposed. Our purpose is to compare the post-operative outcome of sarcopenic and non sarcopenic patients using a simple, available, reproducible and rapid radiological method, which will help the healthcare professionals to rapidly identify high risk patients for possible complicated and long post-operative course allowing them to take appropriate perioperative measures to reduce the risks.

Registry
clinicaltrials.gov
Start Date
March 1, 2022
End Date
May 31, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Hôpital NOVO
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient operated on for colectomy or proctectomy with restoration of continuity for colorectal cancer between 1 January 2020 and 31 December 2021
  • Patient who had a CT scan in the 2 months prior surgery
  • Patient aged 18 years or older

Exclusion Criteria

  • Patients with inflammatory bowel disease (Crohn disease, haemorrhagic rectocolitis)
  • Patients with neuromuscular pathology affecting their mobility
  • Patients who were diagnosed positif to SARS COV 2 before or during hospitalisation
  • Patients who refuse the collection of their data

Outcomes

Primary Outcomes

Comparison of the average postoperative length of stay in sacopenic and non-sarcopenic patients

Time Frame: Until discharge from hospital, an average of 30 days

Comparison of the number of post-operative hospital days between the two groups

Secondary Outcomes

  • Comparison between complication rate in sarcopenic and non sarcopenic patients(At the end of the 30 post-operative days)
  • Assessment of re-hospitalization rate between sarcopenic and non sarcopenic patients(At the end of the 30 post-operative days)
  • Comparison of the length of stay in the rehabilitation center for sarcopenic and non sarcopenic transferred patients(At the end of the 30 post-operative days)
  • Comparison of the transfer rate to rehabilitation or nursing home center between sarcopenic and non sarcopenic patients(At the end of the 30 post-operative days)

Study Sites (1)

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