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临床试验/NCT04654663
NCT04654663已完成不适用

Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB: a Retrospective Study

Yonsei University1 个研究点 分布在 1 个国家目标入组 605 人开始时间: 2020年12月7日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
605
试验地点
1
主要终点
postoperative pulmonary complications : prolonged ventilation

研究概览

简要总结

Retrospective data collection. The aim of this study is to determine the effect of preoperative sarcopenia index on postoperative pulmonary complications in elderly patients undergoing off-pump coronary artery bypass graft surgery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who were 65 years of age or older at the time of surgery(off-pump coronary artery bypass graft surgery)
  • serum cystatin C and creatinine test results were valid within one week before surgery

排除标准

  • Patients with chronic renal failure (estimated glomerular filtration rate less than 60)
  • Patients with acute kidney injury
  • Patients with respiratory tract infection within 1 month before surgery

结局指标

主要结局

postoperative pulmonary complications : prolonged ventilation

时间窗: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

Indicate whether the patient had prolonged post-operative pulmonary ventilation \> 24.0 hours. The hours of postoperative ventilation time include OR exit until extubation, plus any additional hours following reintubation.

postoperative pulmonary complications : pneumonia

时间窗: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

CXR with at least one of the following: infiltrate, consolidation, cavitation;plus at least one of the following: fever \>38 °C with no other cause, white cell count \<4 or\>12\*109 litre-1, \>70 yr of age with altered mental status with no other cause;-plus at least two of the following: new purulent/ changed sputum, increased secretions/suctioning, new/worse cough/dyspnoea/tachypnoea, rales/ bronchial breath sounds, worsening gas exchange.

postoperative pulmonary complications : reintubation

时间窗: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

Indicate whether the patient was intubated for the first time after leaving the OR from the initial procedure, or re-intubated during the hospital stay after the initial extubation.

次要结局

  • postoperative complications : Reoperation due to bleeding/tamponade(During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.)
  • postoperative complications : Renal failure(During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.)
  • postoperative complications : Delirium(During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.)
  • postoperative complications : Mortality(After discharge from the hospital, but before the end of the 30th postoperative day.)
  • postoperative complications : Permanent stroke(During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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