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Clinical Trials/NCT04654663
NCT04654663
Completed
Not Applicable

Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB: a Retrospective Study

Yonsei University1 site in 1 country605 target enrollmentDecember 7, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Coronary Artery Occlusive Disease
Sponsor
Yonsei University
Enrollment
605
Locations
1
Primary Endpoint
postoperative pulmonary complications : prolonged ventilation
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Retrospective data collection. The aim of this study is to determine the effect of preoperative sarcopenia index on postoperative pulmonary complications in elderly patients undergoing off-pump coronary artery bypass graft surgery.

Registry
clinicaltrials.gov
Start Date
December 7, 2020
End Date
January 15, 2021
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients who were 65 years of age or older at the time of surgery(off-pump coronary artery bypass graft surgery)
  • serum cystatin C and creatinine test results were valid within one week before surgery

Exclusion Criteria

  • Patients with chronic renal failure (estimated glomerular filtration rate less than 60)
  • Patients with acute kidney injury
  • Patients with respiratory tract infection within 1 month before surgery

Outcomes

Primary Outcomes

postoperative pulmonary complications : prolonged ventilation

Time Frame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

Indicate whether the patient had prolonged post-operative pulmonary ventilation \> 24.0 hours. The hours of postoperative ventilation time include OR exit until extubation, plus any additional hours following reintubation.

postoperative pulmonary complications : pneumonia

Time Frame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

CXR with at least one of the following: infiltrate, consolidation, cavitation;plus at least one of the following: fever \>38 °C with no other cause, white cell count \<4 or\>12\*109 litre-1, \>70 yr of age with altered mental status with no other cause;-plus at least two of the following: new purulent/ changed sputum, increased secretions/suctioning, new/worse cough/dyspnoea/tachypnoea, rales/ bronchial breath sounds, worsening gas exchange.

postoperative pulmonary complications : reintubation

Time Frame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

Indicate whether the patient was intubated for the first time after leaving the OR from the initial procedure, or re-intubated during the hospital stay after the initial extubation.

Secondary Outcomes

  • postoperative complications : Reoperation due to bleeding/tamponade(During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.)
  • postoperative complications : Renal failure(During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.)
  • postoperative complications : Delirium(During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.)
  • postoperative complications : Mortality(After discharge from the hospital, but before the end of the 30th postoperative day.)
  • postoperative complications : Permanent stroke(During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.)

Study Sites (1)

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