Association of Preoperative Sarcopenia and Intraoperative Hypotension in Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy : Prospective Observational Study

• Conditions: Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy

• Registration Number: NCT05320978
• Lead Sponsor: Yonsei University

Brief Summary

The aim of this study is to determine whether preoperative sarcopenia (low muscle strength/muscle mass) is correlated with time weighted average intraoperative hypotension in patients undergoing minimally invasive pylorus preserving pancreaticoduodenectomy.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-04
• Study First Submitted: 2022-04-03
• Study First Submitted QC: 2022-04-08
• Study First Posted: 2022-04-11
• Study Start: 2022-04-18
• Last Update Submitted: 2022-04-20
• Last Update Posted: 2022-04-21
• Primary Completion: 2024-03-27
• Study Completion: 2024-03-27

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 192

Inclusion Criteria

1. patients 20 years or older who undergo minimally invasive pylorus preserving pancreaticoduodenectomy

Exclusion Criteria

1. emergency surgery
2. patients who cannot read consent forms(e.g., illiterate, foreigner, etc.)
3. patients with cognitive dysfunction
4. pregnant, lactating women
5. When hand grip test cannot be performed
6. patients with atrial fibrillation, moderate or severe valvular heart disease, left ventricular ejection fraction less than 35%

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
time weighted average intraoperative hypotension	Procedure (From the induction of anesthesia to the end of anesthesia)	1) Intraoperative hypotension is defined as a mean blood pressure \< 65 mmHg.

Trial Locations

Locations (1)

Yonsei University Health System, Severance Hospital; 🇰🇷 Seoul, Korea, Republic of