Effect of Left Atrial Appendage Excision on Procedure Outcome in Patients With Persistent and Long-standing Persistent Atrial Fibrillation Undergoing Surgical Ablation

Phase 2

• Conditions: Atrial Fibrillation

• Registration Number: NCT02562391
• Lead Sponsor: Meshalkin Research Institute of Pathology of Circulation

Brief Summary

The aim of this study is to assess the effect of left atrial appendage excision on atrial fibrillation recurrence and incidence of stroke in patients with persistent and long-standing persistent atrial fibrillation undergoing surgical ablation.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-05
• Primary Completion: 2015-05
• Status Verified: 2015-09
• Study First Submitted: 2015-09-24
• Study First Submitted QC: 2015-09-25
• Last Update Submitted: 2015-09-25
• Study First Posted: 2015-09-29
• Last Update Posted: 2015-09-29
• Study Completion: 2017-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

• Patients with persistent and long-standing persistent atrial fibrillation eligible for thoracoscopy surgical ablation
• Signed inform consent

Key

Exclusion Criteria

• Paroxysmal atrial fibrillation
• Contraindications for surgical ablation
• Unwilling to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Atrial fibrillation recurrences	18 months

Trial Locations

Locations (4)

Federal Center of Cardiovascular surgery; 🇷🇺 Krasnoyarsk, Russian Federation

Federal State Institution Clinical Hospital of the Presidental Administration of the RF; 🇷🇺 Moscow, Russian Federation

Scientific center of the cardiovascular surgery named by A.N. Bakulev; 🇷🇺 Moscow, Russian Federation

State Research Institute of CIrculation Pathology; 🇷🇺 Novosibirsk, Russian Federation