Effect of Left Atrial Appendage Velocity on Left Atrial Structure and Function After Radiofrequency Ablation Combined With Left Atrial Appendage Occlusion.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Left Atrial Appendage Velocity
- Sponsor
- The Second Hospital of Hebei Medical University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Changes in the structure of the left atrium
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Radiofrequency ablation of atrial fibrillation combined with left atrial appendage closure can not only improve symptoms in patients with non-valvular atrial fibrillation, but also prevent left atrial appendage thrombosis. The safety and effectiveness of left atrial appendage occlusion have been confirmed by randomized controlled trials and actual experience. Among patients with different left atrial appendage emptying speeds, there are limited studies on the structure and function of the left atrial appendage after LAA closure. In this study, patients with persistent nonvalvular atrial fibrillation were selected for radiofrequency ablation combined with LAA closure. The sinus rhythm was restored after the operation. According to the different emptying speed of the left atrial appendage, they were divided into a high-flow rate group and a low-flow rate group. The differences in the structure and function of the left atrium between the two groups were analyzed.
Investigators
Ruiqin xie
Director of the Department of Cardiology in the Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University
Eligibility Criteria
Inclusion Criteria
- •Patients who received atrial fibrillation radiofrequency ablation combined with left atrial appendage closure.
- •Exclude Criteria
- •Patients with incomplete data.
- •Device embolism.
- •Residual shunt around the device found by transesophageal echocardiography greater than 5 mm.
- •Mitral valve stenosis.
- •Artificial valve.
- •Atrial septal defect.
- •Dilated cardiomyopathy
- •Moderate Severe mitral regurgitation
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Changes in the structure of the left atrium
Time Frame: 1year
Measure the left atrial transverse diameter, anteroposterior diameter, upper and lower diameter.
Changes in the function of the left atrium
Time Frame: 1year
Left atrium volume. Two-chamber and four-chamber left atrium strain and strain rate, left atrium storage function, channel function and pump function.