Backup rate selection during neonatal assist control volume guarantee ventilation: A randomised crossover trial
Not Applicable
Completed
- Conditions
- eonatal ventilationNeonatal ventilationRespiratory - Other respiratory disorders / diseasesReproductive Health and Childbirth - Complications of newborn
- Registration Number
- ACTRN12610000884000
- Lead Sponsor
- Royal Women's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 26
Inclusion Criteria
Stable ventilated infants, ventilated using assist control volume guarantee (AC/VG) for previous 24 hours.
Exclusion Criteria
Ventilator changes in previous 4 hours, pH < 7.2, pCO2>80 mmHg, FiO2 > 0.8, acute pneumothoax/pulmonary interstitial emphysema, significant congenital abnormality, severe PVH, receiving muscle relaxants or morphine infusion > 20 ug/kg/hr
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of ventilator inflations triggered by the the infant identified from the ventilator waveforms/trigger data[These data are measured continually. The outcome is defined as the number of triggered inflations / total number of inflations over the epoch]
- Secondary Outcome Measures
Name Time Method Ventilator parameters determined from the ventilator data including:<br>Rate, mean airway pressure, peak inflating pressure[The data are measure continually over the epoch. Epoch averages will be compared];Measures of cardiorespiratory stability including:<br>FiO2, SpO2, TcCO2, HR and BP assessed using the ventilator data, Masimo Radical pulse oximeter, and Philips Intellivue series monitor with transcutaneous module[These data are recorded every minute. The change over the epoch will be measured (average data from last 2 mins of epoch minus average data from last 2 mins of run in period prior to epoch)]