Multicomponent Exercise in People With Dementia
- Conditions
- Dementia
- Interventions
- Other: Multicomponent exerciseOther: Video home exercise group
- Registration Number
- NCT04951258
- Lead Sponsor
- National Yang Ming Chiao Tung University
- Brief Summary
People with dementia shows a decline in cognition, such as memory, executive function (EF), language, attention, and spatial orientation that is significant enough to interfere with the independence and daily functioning. Previous studies reported that multicomponent exercise improved EF in people with mild cognitive impairment and independence of ADL in those with Alzheimer's disease. However, few studies investigated whether multicomponent exercise improved EF, memory, and ADL in people with dementia. Therefore, the purposes of this study are to examine 1) the effect of multicomponent exercise on EF, memory, and ADL in people with mild to moderate dementia; 2) the correlation between change in EF and ADL; 3) the correlation between change in memory and ADL.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 52
- Age: 60-80 y/o
- Mini-Mental State Examination: 10-26
- Clinical Dementia Rating: 1-2
- Walk at least 6 meters independently (with or without walking aids)
- Any other diagnosis of neurological diseases or musculoskeletal problems (Except dementia)
- Physical or psychological comorbidities that affect performance during assessment or intervention
- Already participating in other physical training in the last 1 month
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Multicomponent exercise group Multicomponent exercise - Video home exercise group Video home exercise group -
- Primary Outcome Measures
Name Time Method Trail making test - Chinese version Change from baseline at 9 week It is a measurement to evaluate cognitive flexibility.
Mini-Mental State Examination Change from baseline at 9 week It is a 30-point questionnaire that is used extensively in clinical and research settings to measure cognitive impairment. Higher scores mean a better outcome.
Chinese version of Stroop color and word test Change from baseline at 9 week It is a measurement to evaluate inhibition control.
Digit span test Change from baseline at 9 week It is a measurement to evaluate working memory.
Chinese version of Verbal learning test Change from baseline at 9 week It is a 9-point measurement to evaluate memory. Higher scores mean a better outcome.
- Secondary Outcome Measures
Name Time Method Berg Balance Scale Change from baseline at 9 week It is a tool to evaluate balance. It is a 14 item list with each item consisting of a five-point ordinal scale ranging from 0 to 4, with 0 indicating the lowest level of function and 4 the highest level of function.
Time up and go test Change from baseline at 9 week It is a test to evaluate functional mobility.
30-second chair stand test Change from baseline at 9 week It is a test to evaluate muscle strength.
Chinese version of Quality of Life in Alzheimer Disease Scale Change from baseline at 9 week It is a measurement to evaluate quality of life. The scale scores range from 13 to 52, with higher scores indicating greater quality of life.
6-minute walk test Change from baseline at 9 week It is a test to evaluate endurance.
Barthel index Change from baseline at 9 week It is a 100-point ordinal scale used to measure performance in activities of daily living. Higher scores mean a better outcome.
Instrumental activities of daily living (IADL) scale Change from baseline at 9 week It is a 24-point ordinal scale used to measure performance in instrumental activities of daily living. Higher scores mean a better outcome.