Short-term Effects of Tai Chi Chuan Exercise on the Regulation of Lipid and Glucose Metabolisms and Endothelial Function

Not Applicable

Completed

• Conditions: Physiological Effect of TCC on Glucose Metabolism
• Interventions: Behavioral: Classical Yang's TCC exercise

• Registration Number: NCT03503084
• Lead Sponsor: Changhua Christian Hospital

Brief Summary

The short term effects of TCC exercise are the significant increase in serum insulin and insulin resistance, and the significant decrease in serum TC, HDL-C, ET-1 and insulin sensitivity in TCC practitioners. TCC might be benefit the health of its practitioners through the regulation of lipid and glucose metabolism and endothelial function.

Detailed Description

Tai Chi Chuan (TCC) has been shown to be beneficial to the health. However, its effects on lipid and glucose metabolism are not fully understood. This study investigated the short term effect of TCC exercise on lipid and glucose metabolism and endothelial function in TCC practitioners. Twenty-one TCC practitioners and nineteen normal controls were included in this study. The hemodynamics, serum insulin, indices of insulin resistance/sensitivity, serum endothelin-1 (ET-1), blood lipids and aldosterone before and 30 min after a rest or a session of classical Yang's TCC exercise were compared.

Study Timeline

• Study Start: 2009-05-01
• Primary Completion: 2009-11-30
• Study Completion: 2009-12-31
• Study First Submitted: 2018-03-30
• Status Verified: 2018-04
• Study First Submitted QC: 2018-04-11
• Last Update Submitted: 2018-04-11
• Study First Posted: 2018-04-19
• Last Update Posted: 2018-04-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• TCC practitioners in a TCC training center in Taiwan over 50 years of age
• Healthy subjects without TCC experience over 50 years of age

Exclusion Criteria

• Subjects who had major cardiopulmonary disease
• Subjects who have diabetes mellitus, renal or liver disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
TCC group	Classical Yang's TCC exercise	Classical Yang's TCC exercise

Primary Outcome Measures

Name	Time	Method
change in quantitative insulin sensitivity check index	before and 30 minutes after the completion of TCC exercise	change in insulin sensitivity due to TCC

Secondary Outcome Measures

Name	Time	Method
change in serum total cholesterol	before and 30 minutes after the completion of TCC exercise	change in serum total cholesterol due to TCC
change in homeostasis model assessment-estimated insulin resistance	before and 30 minutes after the completion of TCC exercise	change in insulin resistance by TCC

Trial Locations

Locations (1)

Wan-An Lu; 🇨🇳 Ilan, Taiwan