Effects of High Functional Resistance Training Program on Arterial Stiffness

Not Applicable

Completed

• Conditions: Training Study

• Registration Number: NCT06935318
• Lead Sponsor: Salisbury University

Brief Summary

Study examined the effects of CrossFit training on blood vessels. The results indicate long term CrossFit training does not harm blood vessel function.

Detailed Description

Arterial stiffness is a systemic loss of elastic properties that significantly augment cardiovascular disease risk in adults. Chronic aerobic and anaerobic exercise activity has consistently been shown to attenuate or not affect markers of arterial stiffness in adults with chronic disease and otherwise healthy adults. Chronic high functional resistance training's effect on vascular compliance is less understood. The study aimed to determine the impact of a chronic high functional resistance training program on pulse wave velocity and beta-stiffness index. Accordingly, participants (18-40 years old) were placed in a non-randomized fashion into high functional resistance training (HIB) group (n = 9; \>6 months of CrossFit experience; 4 female) or control (CON) group (n = 8; \< 6 months of exercise experience; 6 female). Participants in the HIB group trained at the same local facility 4 -5 days a week, utilizing the same training program. CON group refrained from exercise during the study period. Body composition, 1,000-meter rowing test, deadlift 1 repetition maximum (1 RM), hemodynamic assessments, and vascular compliance were assessed at baseline and follow-up.

Study Timeline

• Study Start: 2020-08-29
• Primary Completion: 2023-12-10
• Study Completion: 2024-01-15
• Status Verified: 2025-04
• Study First Submitted: 2025-04-10
• Study First Submitted QC: 2025-04-16
• Last Update Submitted: 2025-04-16
• Study First Posted: 2025-04-20
• Last Update Posted: 2025-04-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

• body weight stability with no more than ± 2.5 kg fluctuations in last six month

Exclusion Criteria

• hypertension
• heart disease
• cancer
• diabetes
• renal disease
• hepatic disorders
• history of tobacco use.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Pulse wave velocity	From enrollment to the end of treatment at 11 weeks

Trial Locations

Locations (1)

Salisbury University; 🇺🇸 Salisbury, Maryland, United States