anguage impairment in the 22q11 deletion syndrome

Completed

• Conditions: developmental language disorder; developmental language impairment; 10057167

• Registration Number: NL-OMON54844
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 24 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Age: 3-6,5 years
Growing up in monolingual, Dutch-speaking families
Patient groups: a diagnosis of 22q11 deletion syndrome OR Specific Language
Impairment (which is not strictly a medical condition)
Control group: healthy, typically developing children; confirmed absence of any
of the above conditions.

Exclusion Criteria

severe hearing loss (35 dB or worse)
growing up in a family in which one or more other languages in addition to
Dutch are regularly used to communicate with the child

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>(1) Similarity/ difference in developmental language profiles of children with<br /><br>22q11DS and children with SLI, in comparison to neurotypical (typically<br /><br>developing) controls.<br /><br>(2a) Similarity / difference of the 22q11DS and SLI groups with respect to<br /><br>neurocognitive mechanisms hypothesized to be critical for language acquisition:<br /><br>short-term/working memory, executive function, and implicit learning.<br /><br>(2b) The degree of association between neurocognitive performance and language<br /><br>outcomes in the 22q11DS and SLI groups. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p><br>