PER-010-99已完成1 期
METHADONE FOR THE TREATMENT OF CHRONIC PAIN CANCER
DROGERIA MARFAN S.A.C.,0 个研究点目标入组 0 人开始时间: 1999年9月27日最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 0 至 0（—）
入选标准
- •1. Patient diagnosed with cancer confirmed by histology
- •2. Age between 18 and 70 years.
- •3. Presence of a pain lasting more than 30 days.
- •4. Pain secondary to cancer or its treatment.
- •5. Somatic, visceral, neuropathic or mixed pain
- •6. Intensity of pain of moderate, intense or very intense degree
- •7. Kamofsky equal to or greater than 60.
- •8. Patients who have used the 1st and 2nd therapeutic steps of the WHO require the use of a strong opioid.
- •9. Patients who accept and can sign an informed consent.
- •10. Patients who can read, write and do not have cognitive impairment.
- •11. Patients able to keep a diary during their participation in the study.
排除标准
- •1. Presence of a pain maintained by the sympathetic. The presence of a pain maintained by the sympathetic is suspected when there is a severe pain, burning-like, associated with allodynia (pain secondary to innocuous stimulation in normal skin), hyperpathy (presence of pain after a stimulus is finished), changes trophic skin and its annexes, hard edema and osteoporosis.
- •2. Vital functions (blood pressure, heart rate and respiratory rate unstable or abnormal.
- •3. Pregnant or lactating patient.
- •4. Presence of liver, kidney or respiratory failure, asthma, chronic obstructive pulmonary disease, intracranial hypertension or a history of paralytic ileus.
- •5. Allergy to morphine or other opioids.
- •6. Patients scheduled for surgery, chemotherapy, radiotherapy or hormonotherapy during the study period.
- •7. Patients who received chemotherapy or radiotherapy, or change in the hormonal regimen in the 14 days prior to the study.
研究者
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