The Effect of Terlipressin on Intesitnal Function in Septic Shock Patients

Not Applicable

• Conditions: Terlipressin; Septic Shock
• Interventions: Drug: Terlipressin; Drug: Norepinephrine

• Registration Number: NCT02306239
• Lead Sponsor: Liu ZiMeng

Brief Summary

Terlipressin becomes a vasopressin for septic shock. But some studies found it may lead to severe intesitnal complications such as intestinal ischemia. The investigators study was designed to find the effect of terlipressin on intestinal function in septic shock patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2014-12
• Study Start: 2014-12
• Study First Submitted: 2014-12-01
• Study First Submitted QC: 2014-12-02
• Study First Posted: 2014-12-03
• Last Update Submitted: 2014-12-25
• Last Update Posted: 2014-12-30
• Primary Completion: 2015-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• septic shock

Exclusion Criteria

• shock due to other reasons
• diagnosited intesitinal ischemia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
terlipressin	Terlipressin	patients received terlipressin
norepinephrine	Norepinephrine	patients received norepinephrine

Primary Outcome Measures

Name	Time	Method
intestinal function assessed by abdominal distension, intestinal bleeding, peritonitis, plasma DAO level, enteral nutrition	7 days

Trial Locations

Locations (1)

the First Affiliated Hospital of Sumyetsan University; 🇨🇳 Guangzhou, Guangdong, China