Embryonic Ploidy Status in the Oncofertility Population
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- embryonic aneuploidy rates
研究概览
简要总结
looking at aneuploidy rates in embryos from patients who are going to or have undergone treatment for a malignancy with gonadotoxic treatment.
详细描述
The study involves oncofertility patients--individuals who are undergoing or have undergone therapy for a malignancy--who are interested in pursuing or preserving fertility. In particular, it investigates chromosomal abnormalities or aneuploidy in the embryos of those individuals as compared to the general infertility population. Embryonic aneuploidy is largely due to reproductive senescence. As such the investigators will discuss oncofertility prevalence and treatment as well as reproductive senescence and assessment of embryonic aneuploidy. The study will seek to determine if there are changes in embryonic aneuploidy rates in oncofertility patients that differ from simple age related risks.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •1.Present or past oncologic diagnosis requiring potentially gonadotoxic treatment
排除标准
- •Oocyte banking
- •Use of oocyte donation
- •Any contraindications to undergoing in vitro fertilization or gonadotropin stimulation
- •Single gene disorder requiring more detailed embryo genetic analysis
结局指标
主要结局
embryonic aneuploidy rates
时间窗: 1 month
to evaluate the incidence of embryonic aneuploidy among oncofertility patients compared to the general infertility population
次要结局
未报告次要终点