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Rapid Structural and Functional Improvements in Following 0.19 mg Fluocinolone Acetonide (FAc) Implant in Diabetic Macular Edema Patients With Poor Visual Acuity: 12-month Audit Results From United Arab Emirates

Conditions
Diabetic Macular Edema
Interventions
Device: 0.19 mg fluocinolone acetonide (FAc) implant
Registration Number
NCT03590587
Lead Sponsor
Benha University
Brief Summary

The Health Authority - Abu Dhabi (HAAD) approved the reimbursement of the slow release FAc implant (ILUVIEN) and it is now available for the treatment of diabetic macular edema (DME) in persons who have been previously treated with a course of corticosteroids and did not have a clinically significant rise in intraocular pressure. We performed a retrospective 12-month audit to assess the efficacy and safety of the FAc implant in our clinical practice.

Detailed Description

Twenty patients with pseudophakic lenses, treated with ILUVIEN, were investigated to evaluate functional and anatomical characteristics and outcomes (visual acuity \[VA; ETDRS letters score\], central macular thickness \[CMT\] and intraocular pressure \[IOP\]) at baseline, weeks 2-4 and months 3, 6 and 12 months.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
30
Inclusion Criteria
  • DME
  • Pseudophakic
Exclusion Criteria
  • Other causes of macular edema.
  • Phakic
  • Know case of gaucoma

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
10.19 mg fluocinolone acetonide (FAc) implantpatients treated with 0.19 mg fluocinolone acetonide (FAc) implant for 12 months
Primary Outcome Measures
NameTimeMethod
BCVA12 months

best corrected visual acuity

Secondary Outcome Measures
NameTimeMethod
IOP12 months

Intraocular pressure

CMT12 months

Central Macular thickness

Trial Locations

Locations (1)

Shiekh Khalifa medical city

🇦🇪

Abu Dhabi, United Arab Emirates

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