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The Surveillance Clinical Study of Rickettsiosis

Recruiting
Conditions
Rickettsiosis
Registration Number
NCT06162975
Lead Sponsor
Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Brief Summary

The purpose of this surveillance (non-interventional) clinical study is to genotype the causative agents of rickettsiosis in biological samples of patients from the Altai Republic, Russian Federation. This is a solely observational study in the patients with diagnosed or suspected tick-borne rickettsioses, with no intervention to the routine treatment and diagnostic process. During the study the medical history, diseases progress and symptoms, as well as treatments are being registered in individual case report forms. The rests of the samples used for standard diagnostics (plasma, or serum, and/or swabs of the tick bite site) are being collected and afterwards will be analyzed for a new rickettsia type. These data will be compared to the medical history and symptoms of the patients in order to identify clinical pattern specific for the new rickettsia type. Informed consents from all patients or their legal representatives are being collecting. The study was approved by the local ethical committee.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Written patient's informed concent for study participation;
  • Male and female patients of any age with diagnosed or suspected tick-born rickettsioses.
Exclusion Criteria
  • Unwillingness to participate in the study by any reason.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Genotype the causative agents of rickettsiosisup to 4 weeks

Genotype the causative agents of rickettsiosis in biological samples (blood and swab) of patients from the Altai Republic, Russian Federation

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Altai Republic Center for HIV prophylaxis and treatment

🇷🇺

Gorno-Altaïsk, Altai Republic, Russian Federation

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