Comparison of Praziquantel with antimalarial drug combinations in the treatment of children with bilharzia in Kirinyaga county, Kenya
- Conditions
- schistosomiasis
- Registration Number
- PACTR202001919442161
- Lead Sponsor
- Kenya Medical Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 540
For participants to be enrolled in the study they have to meet ALL of the following criteria:
•Aged between 6 and 15 years old (confirmed from the date of birth recorded on the school registers),
•Testing positive for S. mansoni infection (confirmed by presence of eggs in stool).
•Residing in Mwea East and Mwea West, Kirinyaga County
•Able to take oral treatment
•Respective parent/ guardian provides written informed consent for the child to participate in the study
•Child provides written assent to participate in the study
Potential participants will be excluded for any of the following reasons:
•Weighing more than 50 kg,
•Haemoglobin level = 5.0g/dL
•Signs of severe malnutrition (defined as severe wasting or MUAC <12cm)
•Hypersensitivity to Artesunates, sulfonamides or praziquantel.
•Use of an anti-malaria or anti-schistosomial drug within 28 days before enrollment in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method