Evaluation of effect of addition of magnesium sulphate to bupivacaine for spinal anaesthesia in pregnant wome
Not Applicable
Completed
- Registration Number
- CTRI/2015/05/005749
- Lead Sponsor
- ady Hardinge Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
ASA I and II parturients
Undergoing lower segment Caesarean section
Exclusion Criteria
patient refusal
any contraindication to regional anaesthesia
weight >90kg
height <145 or >170cm
known allergy to local anaesthetic or magnesium sulphate
dysrrthymias in ECG or any systemic disorder
history of chronic pain
already on magnesium therapy
severe psychiatric disturbance
history of drug abuse
unable to communicate in either hindi or english
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prolongation in duration of postoperative analgesia with addition of intrathecal magnesium sulphate to hyperbaric bupivacaine as compared to hyperbaric bupivacaine with normal salineTimepoint: time interval between administration of intrathecal block and first request for analgesia by patient(visual analog score more than 4 ) was noted
- Secondary Outcome Measures
Name Time Method Onset of sensory & motor block was slower while duration of sensory as well as motor block was prolonged with magnesium sulphate group. Neonatal APGAR scores and incidence of side-effects were comparable in the two groupsTimepoint: Continuous ECG,HR,SpO2 were monitored. Non-invasive BP,PR & level of sedation at every 3min interval till delivery of baby,thereafter at 5min interval till end of surgey,postop at 30min interval for first 2hr then hourly till first recue analgesic <br/ ><br>Onset of sensory block- from time of block till T6(pin-prick method) <br/ ><br>Onset of motor block-till Bromage scale 3 reached <br/ ><br>APGAR score-at 1 and 5 min <br/ ><br>Duration of sensory blocktime till T12 reached <br/ ><br>Duration of motor block-till Bromage scale 0 reached