A clinical trial to study the effect of dexmedetomidine and dexamethasone with ropivacaine to reduce pain in upper limb bone surgeries
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2022/11/047105
- Lead Sponsor
- SRI SIDDHARTHA MEDICAL COLLEGE AND HOSPITAL,TUMKUR
- Brief Summary
A hospital based comparative study of dexmedetomidine vs dexamethasone as an adjuvants for 0.5% ropivacaine in ultrasound guided supraclavicular brachial plexus block.
INTRODUCTION:Ultrasound guided Supraclavicular brachial plexus block (SCPB) is used for upper limb orthopaedics surgeries with ease, reliability, and a few complication rates. Both addition of dexamethasone and dexmedetomidine have been found to prolong the duration of anaesthesia. However, there has been few studies conducted to compare the effects of dexamethasone and dexmedetomidine added as adjuvants to the ropivacaine for supraclavicular brachial plexus block. This study will be conducted with the primary aim of evaluating the effect of dexmedetomidine to that of dexamethasone as a better medication for a prolonged anesthesia and with minimum complications
ASA grade I & II patients aged 18-60 years posted for orthopaedic upper limb surgeries at Sri Siddhartha Medical College and Research Centre, Tumkur will be selected for the study.Period of **24** months with sample size of 60 patients.
All patients as per inclusion and exclusion criteria posted for elective orthopaedics surgical procedures will be taken in the study
METHODOLOGY:
The data is collected by convenient sampling .The data will be entered in Excel spread sheet. Descriptive statistical analysis will be carried out. Quantitative variables will be presented as mean and standard deviation and qualitative variables will be presented as frequency and percentages. The association between categorical variables will be analyzed by applying Chi-square test. The data will be analyzed by using SPSS software (version 20).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 60
•Patients of ASA physical status grade1 and grade2 •Undergoing upper limb surgery under supraclavicular block.
- •Infection at injection site.
- •Pre-existing peripheral neuropathy.
- •History of allergy to any of the study drugs.
- •Peripheral vascular disease.
- •Suspected coagulopathy.
- •Respiratory illness.
- •Uncooperative patients.
- •Unwillingness to give consent.
- •Patient with history of seizures.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the onset and duration of motor blockade 5 10 15 20 minutes after injection
- Secondary Outcome Measures
Name Time Method the duration of sensory and motor blockade 0 4 8 12 hours respectively after injection
Trial Locations
- Locations (1)
SRI SIDDHARTHA MEDICAL COLLEGE AND HOSPITAL
🇮🇳Tumkur, KARNATAKA, India
SRI SIDDHARTHA MEDICAL COLLEGE AND HOSPITAL🇮🇳Tumkur, KARNATAKA, IndiaDR NIRANJAN MPrincipal investigator9500632100niranjanmadevan@gmail.com