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临床试验/CTRI/2022/11/047105
CTRI/2022/11/047105尚未招募不适用

COMPARISION OF DEXMEDETOMIDINE VS DEXAMETHASONE AS AN ADJUVANT FOR 0.5%ROPIVACAINE IN ULTRASOUND GUIDED SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK IN UPPER LIMB ORTHOPAEDICS SURGERIES

SRI SIDDHARTHA MEDICAL COLLEGE AND HOSPITAL,TUMKUR1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2022年5月12日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
the onset and duration of motor blockade

研究概览

简要总结

A hospital based comparative study of  dexmedetomidine vs dexamethasone as an adjuvants for 0.5% ropivacaine in ultrasound guided supraclavicular brachial plexus block.

INTRODUCTION:Ultrasound guided Supraclavicular brachial plexus block (SCPB) is  used for upper limb orthopaedics surgeries with ease, reliability, and a few complication rates. Both addition of dexamethasone and dexmedetomidine have been found to prolong the duration of anaesthesia. However, there has been few studies conducted to compare the effects of dexamethasone and dexmedetomidine added as adjuvants to the ropivacaine for supraclavicular brachial plexus block. This study will be conducted with the primary aim of evaluating the effect of dexmedetomidine to that of dexamethasone as a better medication for a prolonged anesthesia and with minimum complications

ASA grade I & II  patients aged 18-60 years posted for   orthopaedic upper limb  surgeries at Sri Siddhartha Medical College and Research Centre, Tumkur will be selected for the study.Period of 24 months with sample size of 60 patients.

All patients as per inclusion and exclusion criteria posted for elective orthopaedics surgical procedures will be taken in the study

METHODOLOGY:

The data is collected by convenient sampling .The data will be entered in Excel spread sheet. Descriptive statistical analysis will be carried out. Quantitative variables will be presented as mean and standard deviation and qualitative variables will be presented as frequency and percentages. The association between categorical variables will be analyzed by applying Chi-square test. The data will be analyzed by using SPSS software (version 20).

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Open Label

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • •Patients of ASA physical status grade1 and grade2 •Undergoing upper limb surgery under supraclavicular block.

排除标准

  • •Infection at injection site.
  • •Pre-existing peripheral neuropathy.
  • •History of allergy to any of the study drugs.
  • •Peripheral vascular disease.
  • •Suspected coagulopathy.
  • •Respiratory illness.
  • •Uncooperative patients.
  • •Unwillingness to give consent.
  • •Patient with history of seizures.

结局指标

主要结局

the onset and duration of motor blockade

时间窗: 5 10 15 20 minutes after injection

次要结局

  • the duration of sensory and motor blockade(0 4 8 12 hours respectively after injection)

研究者

发起方
SRI SIDDHARTHA MEDICAL COLLEGE AND HOSPITAL,TUMKUR
申办方类型
Private medical college

研究点 (1)

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