Assessing the effectiveness of mouthwashes against SARS-CoV-2 before dental procedures
Not Applicable
Completed
- Conditions
- COVID-19 (SARS-CoV-2 infection)Infections and Infestations
- Registration Number
- ISRCTN16269648
- Lead Sponsor
- York Teaching Hospital NHS Foundation Trust
- Brief Summary
2023 Preprint results in https://doi.org/10.1099/acmi.0.000722.v1 (added 18/12/2023)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
1. Participants aged over 16 years with a positive COVID-19 swab test in the last 72 hours
2. Participants will only be recruited if they are well enough, i.e. only showing mild to moderate symptoms/signs of COVID-19 infection
Exclusion Criteria
1. Refusal of consent
2. Participants known to be pregnant
3. Participants who have allergies to any of the mouthwashes used in the trial
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evels of SARS-CoV-2 in saliva samples measured quantitatively by determining the 50% tissue culture infectious dose (TCID50) and the infectious virus titre in TCID50/ml, at baseline (pre-mouth washing) and 1, 10, 30 and 60 minutes after mouth washing
- Secondary Outcome Measures
Name Time Method There are no secondary outcome measures