Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty

Centre Hospitalier Universitaire, Amiens1 site in 1 country1,500 target enrollmentFebruary 4, 2013

ConditionsMitral Valve Prolapse Mitral Plasty

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Mitral Valve Prolapse
Sponsor: Centre Hospitalier Universitaire, Amiens
Enrollment: 1500
Locations: 1
Primary Endpoint: Survival defines as the time between the date of surgery and the death or date of the last news
Status: Recruiting
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Mitral insufficiency (MI) accounts for 24% of adult valvulopathies and affects 7% of subjects older than 75 years. They are the second leading cause of valvulopathy in Europe. The most common etiology is the associated valvular prolapse. Mitral surgery remains the reference treatment for symptomatic MI. The success of this procedure depends on the mitral valve geometry and the location of the prolapse. The site of the prolapse, whether monovalvular, localized to the posterior or anterior leaflet, or bivalvular, influences the possibilities and probably the long-term results of the plasty.

Registry

clinicaltrials.gov

Start Date

February 4, 2013

End Date

July 4, 2028

Last Updated

2 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Centre Hospitalier Universitaire, Amiens

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Patients operated between 1988 and 2011
•Presence of a valvular prolapse diagnosed by echocardiography
•Possibility of a complete clinical evaluation at the time of the initial echocardiography

Exclusion Criteria

•Ischemic MI (including papillary muscle rupture)
•Presence of significant aortic valvulopathy, mitral valvular stenosis or congenital disease
•History of cardiac surgery