Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty

Recruiting

• Conditions: Mitral Valve Prolapse; Mitral Plasty

• Registration Number: NCT03113552
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

Mitral insufficiency (MI) accounts for 24% of adult valvulopathies and affects 7% of subjects older than 75 years. They are the second leading cause of valvulopathy in Europe. The most common etiology is the associated valvular prolapse. Mitral surgery remains the reference treatment for symptomatic MI. The success of this procedure depends on the mitral valve geometry and the location of the prolapse. The site of the prolapse, whether monovalvular, localized to the posterior or anterior leaflet, or bivalvular, influences the possibilities and probably the long-term results of the plasty.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-02-04
• Study First Submitted: 2017-04-10
• Study First Submitted QC: 2017-04-10
• Study First Posted: 2017-04-13
• Status Verified: 2023-02
• Last Update Submitted: 2023-05-22
• Last Update Posted: 2023-05-23
• Primary Completion: 2028-07-04
• Study Completion: 2028-07-04

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

• Patients operated between 1988 and 2011
• Presence of a valvular prolapse diagnosed by echocardiography
• Possibility of a complete clinical evaluation at the time of the initial echocardiography

Exclusion Criteria

• Ischemic MI (including papillary muscle rupture)
• Presence of significant aortic valvulopathy, mitral valvular stenosis or congenital disease
• History of cardiac surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Survival defines as the time between the date of surgery and the death or date of the last news	6 months

Trial Locations

Locations (1)

CHU Amiens Picardie; 🇫🇷 Amiens, Picardie, France