Clinical study of Wuling capsule combined with nucleoside analogues in the treatment of chronic hepatitis B hypoviremia
Phase 4
- Conditions
- Chronic hepatitis B hypoviremia (syndrome of liver depression and spleen deficiency with blood stasis)
- Registration Number
- ITMCTR2200006471
- Lead Sponsor
- The Third Hospital of Hebei Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
(1) Age 18~65
(2) Patients with chronic hepatitis B hypoviremia (HBV DNA 20~2000 iu/ml) can be diagnosed in combination with previous medical history
(3) TCM syndrome differentiation is liver depression and spleen deficiency with blood stasis;
(4) Patients who voluntarily sign informed consent
Exclusion Criteria
(1) Patients with other virus infections (HAV, HCV, HDV, HEV, CMV, EBV, HIV);
(2) Patients with severe hepatitis and liver cancer such as drug liver, alcoholic liver disease or nonalcoholic fatty liver;
(3) Pregnant or lactating patients;
(4) Patients who have participated in other clinical trials or participated in other drug clinical trials for less than 1 month
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum HBVDNA load;Energy alt, AST, GGT, ALP, TBIL, DBIL;
- Secondary Outcome Measures
Name Time Method TCM symptom score;