CTRI/2022/01/039227
Completed
未知
Efficacy of Nicorandil as an add-on therapy to standard treatment in acute ischemic stroke- A Randomized, single blind, controlled clinical trial - ENCORE
SRMIST0 sites19 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: G94- Other disorders of brain in diseases classified elsewhere
- Sponsor
- SRMIST
- Enrollment
- 19
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 18 \-75 years.
- •\-Both genders.
- •\-Diagnosis of acute ischemic stroke.
- •\-More than 24 hours of onset of symptoms and not greater than 96 hours.
- •\-Modified Rankin scale greater than two.
- •\-Ability to ingest oral medication.
- •\-BMI \>18\.5 kg /m².
Exclusion Criteria
- •Haemorrhagic stroke.
- •Hypotension with a SBP \< 100 mmHg.
- •Patients on ACEIs and ARBs.
- •Patients on steroids.
- •Patients with respiratory compromise.
- •Patients on antidepressant drugs.
- •Severe acid peptic disease.
- •Kidney dysfunction (GFR \< 30ml /min).
- •Intake of NSAID (exemption of Paracetamol).
- •Severe unstable medical illnesses, including uncontrolled cardiac conditions or heart failure, cardiogenic shock (New York Heart Association Class III or IV).
Outcomes
Primary Outcomes
Not specified
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