Comparision of pain relief after total knee replacement surgery between Levobupivacaine(local anaesthetic drug) alone versus Levobupivacaine with Dexmedetomedine(additive)

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2021/10/037439
• Lead Sponsor: KIMS MEDICAL COLLEGE

Brief Summary

This study is a randomised single blinded parallel group comparative trial.We intend to compare the duration of post operative pain relief,side effects,total additional analgesic requirement following continuous adductor canal block in post operative patients who have undergone single knee total knee replacement.we would like to compare levobupivacaine o.25% alone versus 0.25% Levobupivacaine with Dexmedetomedine 0.5 microgram per kg body weight.this is a single centre study done in India in a private medical college with a sample size of 40 participants in each group.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-10-20
• Study Start: 2021-10-24

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients undergoing elective TKR surgeries 2.
• Aged between 18 years and 70 years of age 3.
• American Society of Anesthesiologists (ASA) class 1 to 3.

Exclusion Criteria

• Allergy to local anaesthetic 2.
• Intellectual impairment or psychiatric condition precluding adequate communication 3.
• Bleeding disorder, trauma and infection near the procedure area.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
3.patient satisfaction,	24 HOURS
4.Any adverse effects or complications.	24 HOURS
PRIMARY-1.Duration of analgesia.	24 HOURS
SECONDARY-1.24 hour opioid consumption,	24 HOURS
2.success of early ambulation,	24 HOURS

Secondary Outcome Measures

Name	Time	Method
SECONDARY-1.24 hour opioid consumption,	2.success of early ambulation,

Trial Locations

Locations (1)

KIMS HOSPITAL; 🇮🇳 Bangalore, KARNATAKA, India

KIMS HOSPITAL

🇮🇳Bangalore, KARNATAKA, India

KISHORE KEERTHY N

Principal investigator

9739083518

drkishorekeerthy@gmail.com