Interactions between genetics and diuretic medications in the kidney's clearance of uric acid
Not Applicable
Completed
- Conditions
- GoutRenal and Urogenital - Other renal and urogenital disorders
- Registration Number
- ACTRN12614000871640
- Lead Sponsor
- niversity of Auckland
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
a.Age from 18 to 50 years
b.Able to provide written informed consent
c.eGFR>60
Exclusion Criteria
a.History of gout
b.History of diabetes
c.Fasting capillary glucose >6mmol/L
d.Existing diuretic use
e.Hypokalaemia (serum potassium <3.5mmol/L)
f.Recurrent episodes of vasovagal syncope or fainting
g.Previous intolerance to frusemide
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method