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Clinical Trials/NCT02263482
NCT02263482
Completed
N/A

Inspiratory Muscle and Peripheral Muscle Combined Training Effects on the Respiratory and Functional Capacity and Quality of Life in Chronic Heart Failure

Naomi Kondo Nakagawa1 site in 1 country30 target enrollmentOctober 2012

Overview

Phase
N/A
Intervention
Not specified
Conditions
Chronic Heart Failure
Sponsor
Naomi Kondo Nakagawa
Enrollment
30
Locations
1
Primary Endpoint
Change in respiratory muscle strength (in centimeters of water)
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Heart failure is a clinical syndrome that is the common end of several cardiac diseases with symptoms such as muscle fatigue, dyspnea and reduction of quality of life. To improve respiratory and general functional capacity of these patients, there are strategies that can be used such as inspiratory muscle training and peripheral muscle training (dynamic resistance training).

Detailed Description

After agreement with the written informed consent, 35 subjects with severe heart failure were included in this study. They were randomized in three groups: controls, low-intensity and moderate-intensity group. All volunteers were assessed at Baseline and 8-weeks intervention. Cardiac events were registered following two years from baseline. The present study aimed to assess the effects of a combined program of inspiratory and peripheral muscle training on respiratory and general functional capacity and quality of life in patients with chronic heart failure.

Registry
clinicaltrials.gov
Start Date
October 2012
End Date
December 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Naomi Kondo Nakagawa
Responsible Party
Sponsor Investigator
Principal Investigator

Naomi Kondo Nakagawa

Associate Professor of Medical School of Sao Paulo University

University of Sao Paulo

Eligibility Criteria

Inclusion Criteria

  • chronic heart failure (functional class from NYHA II and III),
  • left ventricle ejection fraction bellow or equal 40%.

Exclusion Criteria

  • uncontrolled arrhythmia
  • pulmonary edema or pulmonary congestion in the last 30 days
  • peripheral oxygen saturation bellow 92% in resting condition
  • respiratory infection in the previous 30 days to the enrollment into the study
  • cognitive, neurological or orthopedic limitations

Outcomes

Primary Outcomes

Change in respiratory muscle strength (in centimeters of water)

Time Frame: Before and after 8-weeks

Inspiratory and expiratory muscle strength was assessed by using a pressure transducer (MVD-300 Microhard System, GlobalMed, Porto Alegre, Brazil).

Secondary Outcomes

  • walking distance(Before and after 8-weeks)

Study Sites (1)

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