RAPID-AF: a novel method to detect paroxysmal atrial fibrillation in primary care and post-stroke patients with no history of AF.
- Conditions
- Atrial fibrillation (NL: boezemfibrilleren)paroxysmal atrial fibrillation (NL: paroxismaal boezemfibrilleren)ischemic stroke (NL: herseninfarct, beroerte)transient ischemic attack (TIA) (NL: TIA).
- Registration Number
- NL-OMON28464
- Lead Sponsor
- Academic Medical Center, Amsterdam, Afdeling Huisartsgeneeskunde, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 1000
Inclusion Criteria
The RAPID-AF study will be performed in two separate cohorts:
(1) consecutive patients presented to the stroke unit of the department of Neurology of the Academic Medical Center (AMC), Amsterdam, and;
Exclusion Criteria
AMC cohort:
- History of atrial fibrillation (AF)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The diagnostic test characteristics of the SRA algorithm of the first 1, 2, 6, 12 and 24 hours of the Holter monitoring (sensitivity, specificity, positive and negative predictive value) for detecting pAF in both primary care patients and post-stroke patients with two weeks continuous Holter monitoring as reference standard for each patient group as well as for the complete cohort.
- Secondary Outcome Measures
Name Time Method - Incidence of AF after 24 hours, 48 hours, 72 hours, one week and two weeks of continuous Holter monitoring in both primary care and post-stroke patients.<br /><br>- A prediction model for pAF including SRA results and patient variables in both primary care and post-stroke patients.<br /><br>- Patient satisfaction for wearing the 14-day Holter monitor.