Identification of a risk profile to guide atrial fibrillation therapy

Completed

• Conditions: Atrial fibrillation; atrial rhythm disorder; 10007521

• Registration Number: NL-OMON35975
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 500

Inclusion Criteria

1. Short-lasting symptomatic paroxysmal or persistent AF
2. Rhythm control strategy is preferred
3. No contra-indication for oral anticoagulation
4. Age > 18 years

Exclusion Criteria

1. Total history of heart failure and/ or of severe valvular disease > 3 years
2. Severe valvular disease
3. Acute coronary syndrome/ myocardial infarction/ percutaneous coronary intervention/ coronary artery bypass
surgery within the past one month
4. Post-operative AF

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Success of rhythm control.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1. Time to recurrence of (a)symptomatic AF.<br /><br>2. Failure of rhythm control, i.e. permanent AF.<br /><br>3. Risk profiles associated with early versus late AF recurrence.<br /><br>4. Progression of paroxysmal AF to persistent or permanent AF and of persistent<br /><br>AF to permanent AF.<br /><br>5. Changes in atrial and ventricular echocardiographic parameters.<br /><br>6. Cardiovascular morbidity and mortality.<br /><br>7. Pulmonary vein ablation.</p><br>